- Hershkovits AS#, Gelley S#, Hanna R, Kleifeld O, Shulman A, Fishman A* (2023) Shifting the balance: soluble ADAM10 as a potential treatment for Alzheimer’s disease. Aging Neurosci. 15:1171123. # equal contribution.
- Yen F-C#, Glusac J#, Baruch L, Davidovich-Pinhas M*, Fishman A*, Machluf M* (2023). Cultured meat prototypes developed through the structuring of edible microcarrier-derived microtissues with oleogel-based fat substitute. Nat Commun. 14:2942. # equal contribution.
- Roulier B#, Rush I#, Lazinski LM, Pérès B, Olleik H, Royal G, Fishman A, Maresca M, Haudecoeur R*. (2023) Resorcinol-based hemiindigoid derivatives as human tyrosinase inhibitors and melanogenesis suppressors in human melanoma cells. Eur J. Med. Chem. 246:114972. # equal contribution.
- Meir I, Alfassi G, Arazi Y, Rein DM, Fishman A, Cohen Y*. (2022) LipaseV catalyzed transesterification of model long-chain molecules in double-shell cellulose-coated oil-in-water emulsion particles as micro-bioreactors. J. Mol. Sci. 23:12122.
- Li W, Fishman A, Achal V*. (2022) Whole cell evaluation and the enzymatic kinetic study of urease from ureolytic bacteria affected by potentially toxic elements. Res. 265:127208.
- Gihaz S, Shrara Herzallh N, Cohen Y, Bachar O, Fishman A*, Yehezkeli O* (2022) The structure of Bilirubin oxidase from Bacillus pumilus reveals a unique disulfide bond for site-specific direct electron transfer. Biosensors 12:258.
- Gelley S, Lankry H, Glusac J, Fishman A.* (2022) Yeast-derived potato patatins: Biochemical and biophysical characterization. Food Chem. 370:130984.
- Argaman O, Ben-Barak Zelas Z, Fishman A, Rytwo G, Radian A.* (2021) Immobilization of aldehyde dehydrogenase on montmorillonite clay using polyethyleneimine as a stabilization and bridging agent. Clay Sci. 212:106216.
- Glusac J, Fishman A*. (2021) Enzymatic and chemical modification of zein for food application. Trends Food Sci Technol. 112:507-517.
- Li W, Fishman A, Achal V*. (2021) Ureolytic bacteria from electronic waste area, their biological robustness against potentially toxic elements and underlying mechanisms. Environ. Manage. 289: 112517.
- Lavy O, Gophna U, Ayali A, Gihaz S, Fishman A, Gefen E*. (2021) The maternal foam plug constitutes a reservoir for the desert locust’s bacterial symbionts. Microbiol. https://doi.org/10.1111/1462-2920.15448.
- Zipori I*, Fishman A, Ben-Barak Zelas Z, Subbotin Y, Dag A. (2021) Effect of postharvest treatments of mechanically harvested ‘Manzanilla’ table olives on product quality. Postharvest Technol. 174: 111462.
- Galili E*, Langgut D, Terral JF, Barazani O, Dag A, Horwitz LK, Ogloblin Ramirez I, Rosen B, Weinstein-Evron M, Chaim S, Kremer E, Lev-Yadun S, Ben-Barak-Zelas Z, Fishman A. (2021) Early production of table olives at a 7th millennium BP submerged site off the Carmel Coast (Israel). Rep. 11:2218.
- Babakobi M, Reshef L, Gihaz S, Belgorodsky B, Fishman A, Bujanover Y, Gophna U.* (2020) Effect of maternal diet and milk lipid composition on the infant gut and maternal milk microbiomes. Nutrients. 12:2539. doi:10.3390/nu12092539.
- Sinha A, Israeli R, Cirigliano A, Gihaz S, Trabelcy B, Braus GH, Gerchman Y, Fishman A, Negri R, Rinaldi T, Pick E.* (2020) The COP9 signalosome mediates the Spt23 regulated fatty acid desaturation and ergosterol biosynthesis. The FASEB Journal. http://dx.doi.org/10.1096/fj.201902487R
- Deri-Zenaty B, Bachar S, Rebroš M, and Fishman A.* (2020) A coupled enzymatic reaction of tyrosinase and glucose dehydrogenase for the production of hydroxytyrosol. Microbiol. Biotechnol. 204:4945-4955.
- Glusac J, Isaschar-Ovdat S, Fishman A.* (2020) Transglutaminase modifies the physical stability and digestibility of chickpea protein-stabilized oil-in-water emulsions. Food Chem. 315:126301.
- Gihaz S, Bash Y, Rush I, Shahar A, Pazy Y, Fishman A.* (2019) Bridges to stability: Engineering disulfide bonds towards enhanced lipase biodiesel synthesis. ChemCatChem. http://dx.doi.org/10.1002/cctc.201901369
- Zvulunov Y, Ben-Barak-Zelas Z, Fishman A, Radian A.* (2019) A self-regenerating clay-polymer-bacteria composite for formaldehyde removal from water. Eng. J. 374:1275-1285.
- Ielo L, Deri B, Germanò MP, Vittorio S, Mirabile S, Gitto R, Rapisarda A, Ronsisvalle S, Floris S, Pazy Y, Fais A, Fishman A, De Luca L.* (2019) Exploiting the 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: design, synthesis, structural insights and biological profile. Eur J. Med. Chem. 178:380-389.
- Glusac J, Isaschar-Ovdat S, Fishman A, Kukavica B.* (2019) Partial characterization of bean and corn root peroxidase and their ability to crosslink potato protein. Biol. Sci. 71(2):293-303.
- Glusac J, Davidesko-Vardi I, Isaschar-Ovdat S, Kukavica B, Fishman A.* (2019) Tyrosinase-crosslinked pea protein emulsions: Impact of zein incorporation. Food Res. Intl. 116:370-378.
- Meshulam-Pascoviche D, Goldstein N, Fishman A, Lesmes U.* (2019) Impact of fatty acids unsaturation on stability and intestinal lipolysis of bioactive lipid droplets. Colloids Surf. A Physicochem. Eng. Asp. 561:70-78.
- Nikolaivits E, Dimarogona M, Karagiannaki I, Chalima A, Fishman A, Topakas E.* (2018) Characterization and protein engineering of a novel versatile fungal polyphenol oxidase with chlorophenol bioremediation potential. Environ. Microbiol. 84:e01628-18.
- Gihaz S, Kanteev M, Pazy Y, Fishman A.* (2018) Filling the void: Introducing aromatic interactions into solvent tunnels to enhance lipase stability in methanol. Environ. Microbiol. 84:e02143-18. Selected for inclusion in the “Spotlight” of the issue as an article with significant interest.
- Ferroa S, Deri B§, Germanòa MP, Gitto R, Ielo L, Buemia MR, Certoc G, Vittorioa S, Rapisarda A, Pazy Y, Fishman A, De Luca L.* (2018) Targeting tyrosinase: development and structural insights of novel inhibitors bearing arylpiperidine/arylpiperazine fragment. J Med Chem. 61:3908-3917.
- Glusac J, Davidesko-Vardi I, Isaschar-Ovdat S, Kukavica B, Fishman A.* (2018) Gel-like emulsions stabilized by tyrosinase-crosslinked potato and zein proteins. Food Hydrocolloid. 82:53-63.
- Bregman-Cohen A, Deri B, Maimon S, Pazy Y, Fishman A.* (2018) Altering 2-hydroxybiphenyl 3-monooxygenase regioselectivity by protein engineering for the production of a new antioxidant. ChemBioChem 19:583-590.
- Isaschar-Ovdat S, Fishman A.* (2018) Crosslinking of food proteins mediated by oxidative enzymes. Trends Food Sci. Technol. 72:134-143.
- Glusac J, Isaschar-Ovdat S, Kukavica B, Fishman A.* (2017) Oil-in-water emulsions stabilized by tyrosinase-crosslinked potato protein. Food Res. Int. 100:407-415.
- Isaschar-Ovdat S, Fishman A.* (2017) Mechanistic insights into tyrosinase-mediated crosslinking of soy glycinin derived peptides. Food Chem. 232:287-594.
- Javitt G, Ben-Barak Zelas Z, Jerabek-Willemsen M, Fishman A.* (2017) Constitutive expression of active microbial transglutaminase in Escherichia coli and comparative characterization to a known variant. BMC Biotechnol. 17:23-33.
- Ferro S, De Luca L, Germanò MP, Buemi MR, Certo G, Ielo L, Kanteev M, Fishman A, Rapisarda A, and Gitto R. (2017) Chemical exploration of 4-(4-fluorobenzyl)piperidine fragment for the development of new tyrosinase inhibitors. J. Med. Chem. 125:992-1001.
- Gihaz S, Weiser D, Kanteev M, Dror A, Sátorhelyi P, Poppe L, and Fishman A. (2016) Creating an efficient methanol-stable biocatalyst by protein and immobilization engineering–steps towards efficient biosynthesis of biodiesel. ChemSusChem. 9:3161-3170. Marked by editor as VIP (very important paper).
- Deri B, Kanteev M, Goldfeder M, Lecina D, Guallar V, Adir N, Fishman A. (2016) The unravelling of the complex pattern of tyrosinase inhibition. Sci. Rep. 6, 34993; doi: 10.1038/srep34993.
- Isaschar-Ovdat S, Davidovich-Pinhas M, and Fishman A. (2016) Modulating the gel properties of soy glycinin by crosslinking with tyrosinase. Food Res. Int. 87:42-49.
- Kanteev, M., Bregman-Cohen, A., Shahar, A., Adir, N. and Fishman, A. (2015) Structure Food Res Intl 2016 87-42_49determination of wild type and variants of 2-hydroxybiphenyl 3-monooxygenase from Pseudomonas azelaica HPB1. BBA – Proteins and Proteomics. 1854:1906-1913.
- Kanteev, M., Goldfeder, M. and Fishman, A. (2015) Structure-function correlations in tyrosinases. Protein Sci. 24: 1360–1369.
- Dror, A., Kanteev, M., Kagan, I., Gihaz, S., Shahar, A. and Fishman, A. (2015) Structural insights on lipase T6 variants with improved stability in methanol. Appl. Microbiol. Biotechnol. 99: 9449-9461.
- Achmon, Y. and Fishman, A. (2015) The antioxidant hydroxytyrosol: biotechnological production challenges and opportunities Appl. Microbiol. Biotechnol . 99:1119-1130.
- Kuplennik, N., Tchoudakov, R., Ben-Barak Zelas, Z., Sadovski, A. and Fishman, A. (2015) Antimicrobial packaging based on linear low-density polyethylene compounded with potassium sorbate Food Sci. Technol . 62:278-286.
- Gefen, E.*, Talal, S., Brendzel, O., Dror, A. and Fishman, A. (2015) Variation in quantity and composition of cuticular hydrocarbons in scorpion Butus occitanus (Buthidae) in response to acute exposure to desiccation stress Comp. Biochem. Physiol., A: Comp. Physiol . 182:58-63.
- Hosseini, A., Brouk, M., Lucas, M.F., Glaser, F., Fishman, A.* and Guallar, V.* (2015) An atomic picture of ligand migration in toluene 4-monooxygenase J. Phys. Chem. B. . 119:671-678.
- Isaschar-Ovdat, S., Rosenberg, M., Lesmes, U. and Fishman, A. (2015) Characterization of oil-in-water emulsions stabilized by tyrosinase-crosslinked soy glycinin Food Hydrocolloid . 43:493-500.
- Goldfeder, M., Kanteev, M. Isaschar-Ovdat, S., Adir, N.* and Fishman, A.* (2014) Determination of tyrosinase substrate binding modes reveals the mechanistic differences between type-3 copper proteins Nat. Commun . DOI 10.1038/ncomms5505.
- Bernath-Levin, K., Shainsky, J., Sigawi, L. and Fishman, A. (2014) Directed evolution of nitrobenzene dioxygenase for the production of the antioxidant hydroxytyrosol Appl. Microbiol. Biotechnol . 98:4975-4985.
- Dror, A., Shemesh, E., Dayan, N. and Fishman, A. (2014) Engineering lipase from Geobacillus stearothermophilus for improved stability in methanol Appl. Environ. Microbiol . 80:1515-1527.
- Goldfeder, M. and Fishman, A. (2014) Modulating enzyme activity using ionic liquids or surfactants Appl. Microbiol. Biotechnol. 98:545-554.
- Achmon, Y., Ben-Barak Zelas, Z. and Fishman, A. (2014) Cloning Rosa hybrid phenylacetaldehyde synthase for the production of 2-phenylethanol in a whole cell Escherichia coli system Appl. Microbiol. Biotechnol . 98:3603-3611.
- Kanteev, M., Goldfeder, M., Chojnacki, M., Adir, N. and Fishman, A. (2013) The mechanism of copper uptake by tyrosinase from Bacillus megaterium J. Biol. Inorg. Chem . 18:895-903.
- Shainsky, J., Bernath-Levin, K., Isaschar-Ovdat, S., Glaser, F., and Fishman, A. (2013) Protein engineering of nitrobenzene dioxygenase for enantioselective synthesis or chiral sulfoxides. Prot. Eng. Des. Select . 26:335-345.
- Goldfeder, M., Kanteev, M., Adir, N. and Fishman, A. (2013) Influencing the monophenolase/diphenolase activity ratio in tyrosinase BBA-Proteins and Proteomics . 1834:629-633.
- Dror, A. and Fishman, A. (2012) Engineering non-heme mono- and dioxygenases for biocatalysis Comput. Structur. Biotechnol. J . 2(3):e201209011.
- Goldfeder M, Egozy M, Shuster V, Adir, N. and Fishman A. (2012) Changes in tyrosinase specificity by ionic liquids and sodium dodecyl sulfate Appl. Microbiol. Biotechnol . 97:1953-1961.
- Brouk, M. and Fishman, A. (2012) Improving process conditions of hydroxytyrosol synthesis by toluene-4-monooxygenase J. Mol. Catal. B:Enzymatic . 84:121-127.
- Achmon, Y., Goldshtein, J., Margel, S., and Fishman, A. (2011) In situ removal of 2-phenylethanol from yeast fermentation using hydrophobic microspheres J Microencapsulation . 28:628-638.
- Sendovski, M., Kanteev, M., Shuster Ben-Yosef, V., Adir, N., and Fishman, A. (2011) First structures of Bacillus megaterium tyrosinase reveal plasticity in copper binding J Mol Biol. 405:227-237.
- Shuster Ben-Yosef, V., Sendovski, M., and Fishman, A. (2010) Directed evolution of tyrosinase from Bacillus megaterium for enhanced diphenolase activity Enzyme Microbiol Technol . 47:372-376.
- Sendovski, M., Kanteev, M., Shuster Ben-Yosef, V., Adir, N., and Fishman, A. (2010) Crystallization and preliminary x-ray crystallographic analysis of a bacterial tyrosinase from Bacillus megaterium Acta Crystallography F . 66:1101-1103.
- Brouk, M., Nov, Y., and Fishman, A. (2010) Improving biocatalyst performance by integrating protein engineering and statistical methods Appl Environ Microbiol . 76:6397-6403.
- Brouk, M., Derry, N.-L., Shainsky, J., Ben-Barak Zelas, Z., Boyko, Y., Dabush, K. and Fishman, A. (2010) The influence of key residues in the tunnel entrance and the active site on activity and selectivity of toluene 4-monooxygenase J Mol Catal B:Enzymatic . 66:72-80.
- Sendovski, M., Nir, N. and Fishman, A. (2010) Bioproduction of 2-phenylethanol in a biphasic ionic liquid-aqueous system J. Agric. Food Chem . 58:2260-2265.
- Shainsky, J., Derry N-L., Leichtmann, Y., Wood, T.K., and Fishman A. (2009) Rapid methods for high throughput detection of sulfoxides Appl. Environ. Microbiol . 75:4711-4719.
- Shuster, V. and Fishman, A. (2009) Isolation, cloning and characterization of a tyrosinase with improved activity in organic solvents from Bacillus megaterium J. Mol. Microbiol. Biotechnol . 17:188-200.
- Eshkol, N., Sendovski, M., Bahalul, M., Katz-Ezov, T., Kashi, Y., and Fishman, A. (2009) Production of 2-phenylethanol from L-phenylalanine by a stress tolerant Saccharomyces cerevisiae strain. J. Appl. Microbiol . 106:534-542.
- Brouk, M., and Fishman, A. (2009) Protein engineering of toluene monooxygenases for synthesis of hydroxytyrosol Food Chem. 116:114-121.
- Nir, N., Bahalul, M., Feingersch, R., Katz-Ezov, T., Kashi, Y., and Fishman, A. (2008) Improvement of natural isolates of Saccharomyces cerevisiae strains for synthesis of (S)-4-chloro-3-hydroxybutanoic acid ethyl ester by classic genetics. Appl. Micrbiol. Biotechnol. 78:659-667.
- Feingersch, R., Shainsky, J., Wood, T.K., and Fishman, A. (2008) Protein engineering of toluene monooxygenases for synthesizing chiral sulfoxides. Appl. Environ. Microbiol. 74:1555-1566.
- Fishman, A., Tao, Y., Rui, L., and Wood, T.K. (2005) Controlling the regiospecific oxidation of aromatics via active site engineering of toluene para-monooxygenase of Ralstonia pickettii PKO1. J. Biol. Chem. 280:506-514.
- Fishman, A., Tao, Y., and Wood, T.K. (2004) Physiological relevance of successive hydroxylations of toluene by toluene para-monooxygenase of Ralstonia pickettii PKO1. Biocatal. Biotrans. 22:283-289.
- Fishman, A., Tao, Y., Bentley, W.E., and Wood, T.K. (2004) Protein engineering of toluene 4-monooxygenase of Pseudomonas mendocina KR1 for synthesizing 4-nitrocatechol from nitrobenzene. Biotechnol. Bioeng. 87:779-790.
- Rui, L., Kwon, Y., Fishman, A., Reardon, K.F., and Wood, T.K. (2004) Saturation mutagenesis of toluene ortho-monooxygenase of Burkholderia cepacia G4 for enhanced 1-naphthol synthesis and chloroform degradation. Appl. Environ. Microbiol. 70: 3246-3252.
- Fishman, A., Tao, Y., and Wood, T.K. (2004) Toluene 3-monooxygenase of Ralstonia pickettii PKO1 is a para-hydroxylating enzyme. J. Bacteriol. 186 (10):3117.
- Tao, Y., Fishman, A., Bentley, W.E., and Wood, T.K. (2004) Altering toluene 4-monooxygenase from Pseudomonas mendocina KR1 by active site engineering for the synthesis of 3-methoxycatechol, methoxyhydroquinone, and methylhydroquinone. J. Bacteriol. 186 (14): 4705-4713.
- Tao, Y., Fishman, A., Bentley, W.E., and Wood, T.K. (2004) Oxidation of benzene to phenol, catechol and 1,2,3,-trihydroxybenzene by toluene-4-monooxygenase of Pseudomonas mendocina KR1 and toluene-3-monooxygenase of Ralstonia pickettiiPKO1. Appl. Environ. Microbiol. 70: 3814-3820.
- Fishman, A. and Cogan, U. (2003) Bio-imprinting of lipases with fatty acids. J. Mol. Catal. B:Enzymatic. 22:193-202.
- Fishman, A., Levy, I., Cogan, U., Shoseyov, O. (2002) Stabilization of horseradish peroxidase in aqueous-organic media by immobilization onto cellulose using a cellulose-binding-domain J. Mol. Catal. B:Enzymatic. 18:115-125.
- Fishman, A., Eroshov, M., Sheffer Dee-Noor, S., van Mil, J., Cogan, U. and Effernberger, R. (2001) A two step enzymatic resolution process for large-scale production of (S)- and (R)-ethyl-3-hydroxybutyrate. Biotechnol. Bioeng. 74:256-263.
- Shapira-Levinger, M. and Fishman, A. (2000) Kinetic resolution of a diltiazem intermediate by lipase-catalyzed enantioselective alcoholysis. J. Mol. Catal. B: Enzymatic. 9:251-257.
- Fishman, A., Kellner, D., Ioffe, D., Shapiro, E. (2000) A practical chemo-enzymatic process for the preparation of (1R,cis)-2-(2,2-dihaloethenyl)-3,3-dimethylcyclopropane carboxylic acids. Org. Proc. Res. Develop. 4
- Fishman, A., Basheer, S., Shatzmiller, S. and Cogan, U. (1998) Fatty-acid-modified enzymes as effective enantioselective catalysts in microaqueous organic media. Biotechnol. Lett. 20(6): 535-538.
- Fishman, A. and Zviely, M. (1998) Chemo-enzymatic synthesis of (S)-a-cyano-3-phenoxybenzyl alcohol. Tetrahedron:Asymmetry. 9:107-118.
- Fishman, A., Berk Z. and Shoham Y. (1995) Large scale purification of xylanase T-6. Appl. Microbiol. Biotechnol. 44:88-93.